Clinical Lab Handbook

Urine- Timed or Random sample submitted in sterile cup (No preservative)

Stability: Samples can be stored at room temperature or refrigerated for up to 24 hours

The technique of freezing-point depression is used to measure osmolality. Osmolality is the total solute concentration of an aqueous solution or the measure of the number of dissolved solute particles in solution. Osmometers measure the number of solute particles irrespective of molecular weight or ionic charge. Advanced Osmometers utilize high precision thermistors to sense the sample temperature, to control the degree of supercooling and freeze induction, and to measure the freezing point of the sample.

Osmolality can assist in the proper diagnosis and treatment of patients with disorders involving water and electrolyte imbalances. It is also useful in the evaluation of patients suspected of having ingested a toxin such as the alcohols methanol, ethanol, and isopropanol; ethylene and propylene glycol; salicylic acid; and paraldehyde.

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